If it's good enough for Madge and La Paltrow, isn't it good enough for you? The modernist luxury and stellar service bring in the celebs; not for nothing, it also serves as a key event venue during the annual Berlin Film Festival. Location wise, you really can't be better based for a Berlin visit, smack in Mitte (within walking distance to the Brandenburg Gate, the Reichstag, and the Tiergarten) with both the Schöneberg and Kreuzberg nabes just a little farther afield (and easily reachable on public transport).